Product Name :
RBX1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
BA554C12.1 antibody E3 ubiquitin-protein ligase RBX1 antibody FLJ60363 antibody MGC13357 antibody MGC1481 antibody OTTHUMP00000028983 antibody Protein ZYP antibody Rbx 1 antibody Rbx1 antibody RBX1_HUMAN antibody 展开
Function :
Rbx1 (also designated ROC1 and Hrt1) and the closely related protein Rbx2 (also designated ROC2) are RING finger containing homologs of the yeast protein APC11, a member of the anaphase-promoting complex (APC). Rbx1 was shown to be a component of the von Hippel-Lindau (VHL) transcription elongation complex, which includes VHL, Elongin B, Elongin C and Cullin-2. Rbx1 interacts with Cullin-1 in the SCF (Skp1-Cdc53-F-box protein) ubiquitin ligase complex (2-4). Rbx1 functions as a common subunit of SCF complexes required for ubiquination of various proteins including yeast G1 cyclins, IkBa and b-catenin (2-4). Rbx1 was shown to enhance the ubiquitin ligase activity of the VHL/Cullin-2 complex, and of the SCF/Cullin-1 complex.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within Human RBX1 aa 1-108 / 108.
Species reactivity:
Human, Mouse
Verify application:
WB, IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069189
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Formula of 5-Hydroxymethylfurfural Aliquot store at -20℃ or -80℃.1430219-73-0 custom synthesis Avoid repeated freeze / thaw cycles.PMID:33570698
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 12 kDa
Positive control :
HepG2 cell lysate, 293T, MCF-7, human colon cancer tissue, human stomach cancer tissue, mouse colon tissue, human placenta tissue.