Product Name :
2-Hexynyl-5′-N-ethylcarboxamidoadenosine (CAS 141018-30-6)
Synonym :
2-Hexynyl-5?-N-ethylcarboxamidoadenosine; 2-Hexynyl-NECA; HENECA
Application :
2-Hexynyl-5′-N-ethylcarboxamidoadenosine is a high affinity adenosine A1/A2 ligand
CAS:
141018-30-6
Purity:
Molecular Weight:
388.5-Chloro-1-ethyl-4-nitro-1H-imidazole Chemical name 42
Formula :
C18H24N6O4
Physical state:
Solid
solubility :
Soluble in DMSO (100 mM), methanol, and water (100 mM).
Shipping Condition :
Store at 4° C
Melting point:
180-182° C
SMILES:
CCCCC#CC1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)C(=O)NCC)O)O
References:
:Adenosine inhibits TNF alpha -induced MMP-3 production in MH7A rheumatoid arthritis synoviocytes via A2A receptor signaling.261768-25-6 uses | Konishi, H.PMID:33626991 , et al. 2022. Sci Rep. 12: 6033. PMID: 35410356Purinergic signaling: a potential therapeutic target for ischemic stroke. | Wang, L., et al. 2023. Purinergic Signal. 19: 173-183. PMID: 36370253Adenosine 2A Receptor Activation Amplifies Ibrutinib Antiplatelet Effect; Implications in Chronic Lymphocytic Leukemia. | Elaskalani, O., et al. 2022. Cancers (Basel). 14: PMID: 36497231