Product Name :
SAMD9 Recombinant Rabbit Monoclonal Antibody [PSH02-75]
Predicted band size :
184 kDa
Observed band size :
184 kDa
Synonyms:
C7orf5 antibody DRIF1 antibody expressed in aggressive fibromatosis antibody KIAA2004 antibody NFTC antibody OEF1 antibody OEF2 antibody SAM domain-containing protein 9 antibody SAMD9 antibody SAMD9_HUMAN antibody 展开
Function :
Double-stranded nucleic acid binding that acts as a an antiviral factor by playing an essential role in the formation of cytoplasmic antiviral granules. May play a role in the inflammatory response to tissue injury and the control of extra-osseous calcification, acting as a downstream target of TNF-alpha signaling. Involved in the regulation of EGR1, in coordination with RGL2.4-Bromo-5-chloronaphthalen-2-ol site May be involved in endosome fusion. Widely expressed. Very low levels are detected in skeletal muscle. Not detected in brain. Down-regulated in aggressive fibromatosis, as well as in breast and colon cancers. Up-regulated in fibroblasts from patients with normophosphatemic tumoral calcinosis (NFTC). Up-regulated by TNF-alpha through p38 MAPKs and NF-kappa-B. Up-regulated by osmotic shock. Induced by IFNG.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within human SMAD9 aa 1-250 / 1,589.
Species reactivity:
Human
Verify application:
WB, IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
PSH02-75
RRID:
AB_3072965
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Formula of 145508-94-7 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.PMID:33618410
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 184 kDa
Positive control :
A549 cell lysate, HeLa cell lysate, A431 cell lysate, Raji cell lysate, HEK-293 cell lysate, MCF7 cell lysate, HepG2 cell lysate, HCT 116 cell lysate, U-87 MG cell lysate, A431, human skin tissue.