Product Name :
2-Hydroxy Atorvastatin Lactone (CAS 163217-74-1)
Synonym :
Atorvastatin 2-Hydroxy Lactone
Application :
2-Hydroxy Atorvastatin Lactone is a selective and competitive HMGCR (HMG-CoA reductase) inhibitor
CAS:
163217-74-1
Purity:
Molecular Weight:
556.62
Formula :
C33H33FN2O5
Physical state:
Solid
solubility :
Soluble in DMF, DMSO, Ethyl Acetate and Methanol
Shipping Condition :
Store at -20° C
Melting point:
96-102° C
SMILES:
CC(C)C1=C(C(=C(N1CC[C@@H]2C[C@H](CC(=O)O2)O)C3=CC=C(C=C3)F)C4=CC=CC=C4)C(=O)NC5=CC=CC=C5O
References:
:Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin.Formula of 1505818-73-4 | Jacobsen, W.2-(Aminooxy)ethanamine dihydrochloride Chemscene , et al.PMID:33627038 2000. Drug Metab Dispos. 28: 1369-78. PMID: 11038166