Product Name :
3,5-Di-tert-butyl-4-hydroxybenzoic acid (CAS 1421-49-4)

Synonym :

Application :

CAS:
1421-49-4

Purity:

Molecular Weight:
250.33

Formula :
C15H22O3

Physical state:
Solid

solubility :

Shipping Condition :
Store at room temperature

Melting point:
206-209° C (lit.)

SMILES:
CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C(=O)O

References:
:Infrared and Raman Spectra of a Single Resin Bead for Analysis of Solid-Phase Reactions and Use in Encoding Combinatorial Libraries. | Rahman, SS., et al. 1998. J Org Chem. 63: 6196-6199. PMID: 11672249The metabolism of 3:5-di-tert.-butyl-4-hydroxytoluene and 3:5-di-tert.-butyl-4-hydroxybenzoic acid in the rabbit. | Dacre, JC. 1961. Biochem J. 78: 758-66. PMID: 16748891The metabolism of 2,6-di-tert.-butyl-4-hydroxymethylphenol (Ionox 100) in the dog and rat. | Wright, AS., et al. 1965. Biochem J. 97: 303-10. PMID: 16749118Phenol-based lipophilic fluorescent antioxidant indicators: a rational approach. | Krumova, K., et al. 2009. J Org Chem. 74: 3641-51. PMID: 19364120Novel compounds designed as antistress agents. | Tsiakitzis, KC., et al. 2009. J Med Chem. 52: 7315-8. PMID: 19863055Further metabolism of 3,5-di-tert-butyl-4-hydroxybenzoic acid, a major metabolite of butylated hydroxytoluene, in rats. | Yamamoto, K., et al. 1991. Chem Pharm Bull (Tokyo).36805-97-7 Molecular Weight 39: 512-4. PMID: 2054880Bismuth-based cyclic synthesis of 3,5-di-tert-butyl-4-hydroxybenzoic acid via the oxyarylcarboxy dianion, (O2CC6H2(t)Bu2O)2-. | Kindra, DR. and Evans, WJ. 2014. Dalton Trans. 43: 3052-4. PMID: 24336959Synthesis of new 2,5-di-substituted 1,3,4-oxadiazoles bearing 2,6-di-tert-butylphenol moieties and evaluation of their antioxidant activity. | Shakir, RM., et al. 2014. Molecules. 19: 3436-49. PMID: 24658568Dual antioxidant structures with potent anti-inflammatory, hypolipidemic and cytoprotective properties. | Theodosis-Nobelos, P., et al. 2017. Bioorg Med Chem Lett.98977-36-7 web 27: 4800-4804.PMID:33712863 PMID: 29017787Design of Multifaceted Antioxidants: Shifting towards Anti-Inflammatory and Antihyperlipidemic Activity. | Tzara, A., et al. 2021. Molecules. 26: PMID: 34443516Genome and Metabolome MS-Based Mining of a Marine Strain of Aspergillus affinis. | Gonçalves, MFM., et al. 2021. J Fungi (Basel). 7: PMID: 34947073The metabolism of 3,5-di-tert.-butyl-4-hydroxytoluene in the rat and in man. | Daniel, JW., et al. 1968. Biochem J. 106: 783-90. PMID: 5637363The fate of di-(3,5-di-tert.-butyl-4-hydroxyphenyl)methane (Ionox 22) in the rat. | Wright, AS., et al. 1966. Biochem J. 99: 146-54. PMID: 5965331The metabolism of di-(3,5-di-tert.-butyl-4-hydroxybenzyl) ether (Ionox 201) in the rat. | Wright, AS., et al. 1967. Biochem J. 102: 351-61. PMID: 6030293